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Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates

✍ Scribed by Salvatore Valitutti; Sabina Müller; Mark Dessing; Antonio Lanzavecchia

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 549 KB
Volume: 26
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.1830260907

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## Abstract Dendritic cells make up less than 1% of the cells in lymph nodes and tissues, but they are critical in initiating and directing T cell immune responses. In the gut, with exposure to myriad food and bacterial antigens, they probably control T cell unresponsiveness to food antigens and T