The products of a wide variety of organic reactions were rapidly identified by their masses through a combination of thin layer chromatography (TLC) and matrix-assisted laser desorption/ionization time-offlight mass spectrometry (MALDI-TOFMS). Crude mixtures of peptides and glycopeptides, complex ca
Side Reactions in Chain-End Sulfonated Polystyrene via Thin Layer Chromatography Coupled with Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry
β Scribed by Ji, Haining; Nonidez, William K.; Mays, Jimmy W.
- Book ID
- 118047493
- Publisher
- Taylor and Francis Group
- Year
- 2002
- Tongue
- English
- Weight
- 238 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1023-666X
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## Abstract A novel means of combining thinβlayer chromatography (TLC) with laser desorption/ionization mass spectrometry using a liquid matrix is proposed. Surfaceβassisted laser desorption/ionization (SALDI) mass spectrometry, which uses a mixture of a micrometerβsized carbon powder (graphite or
This study presents an in situ determination of organic reaction products on a thin layer chromatography (TLC) plate using surface-assisted laser desorption/ionization (SALDI) time-of-flight mass spectrometry. This technique can rapidly identify products and byproducts on an intact TLC plate. The ch