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Sickle cell-?+-thalassaemia: A haematological and clinical study in Liberia

✍ Scribed by Bienzle, U. ;Kappes, R. ;Reimer, A. ;Feldheim, M. ;Tischendorf, F. W. ;Kohne, E.

Book ID
104720746
Publisher
Springer-Verlag
Year
1983
Weight
354 KB
Volume
47
Category
Article
ISSN
1432-0584

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✦ Synopsis

Clinical and haematological features of 20 patients of several Liberian ethnic groups with sickle cell-beta +-thalassaemia are reported. Haemoglobin analysis showed increased Hb A2 values, high Hb A levels (median 25%), variable amounts of Hb F and a slight imbalance of non alpha/alpha globin chain synthesis ratios. The clinical and other haematological findings varied but the disease seems to run a relatively mild course in the majority of the patients.

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