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Fetal haemoglobin augmentation in E/β0 thalassaemia: clinical and haematological outcome

✍ Scribed by Sylvia T. Singer; Frans A. Kuypers; Nancy F. Olivieri; David J. Weatherall; Robert Mignacca; Thomas D. Coates; Sally Davies; Nancy Sweeters; Elliott P. Vichinsky; the E/β0 Thalassaemia Study Group

Book ID: 108673452
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 171 KB
Volume: 131
Category: Article
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2005.05768.x

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Clinical and haematological features of 20 patients of several Liberian ethnic groups with sickle cell-beta +-thalassaemia are reported. Haemoglobin analysis showed increased Hb A2 values, high Hb A levels (median 25%), variable amounts of Hb F and a slight imbalance of non alpha/alpha globin chain