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Shoulder exostoses in hereditary multiple exostoses: probability of surgery and malignant change

✍ Scribed by Nicholas David Clement; Che E. Ng; Daniel E. Porter


Book ID
116700129
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
341 KB
Volume
20
Category
Article
ISSN
1532-6500

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Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by growth of benign bone tumors. Three chromosomal loci have been implicated in this genetically heterogeneous disease: EXT1 at 8q24, EXT2 at 11p13, and EXT3 on 19p. EXT1 and EXT2 were recently cloned. We evaluated 3