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Should N-acetylcysteine be used in treatment of non-acetaminophen pediatric acute liver failure?

✍ Scribed by Kumar, Vikram

Book ID
121612771
Publisher
Indian Academy of Pediatrics
Year
2013
Tongue
English
Weight
209 KB
Volume
50
Category
Article
ISSN
0019-6061

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Acute liver failure (ALF) carries a high mortality in children. N-acetylcysteine (NAC), an antioxidant agent that replenishes mitochondrial and cytosolic glutathione stores, has been used in the treatment of late acetaminophen-induced ALF and non-acetaminophen-induced ALF. In our unit, NAC was intro