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N-acetylcysteine in non-acetaminophen induced acute liver failure in children

✍ Scribed by Sameer Gupta; Marla Gerrek; Steve Czinn; Christopher Siegel; Samra S Blanchard∗

Book ID
119392955
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
22 KB
Volume
97
Category
Article
ISSN
0002-9270

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Acute liver failure (ALF) carries a high mortality in children. N-acetylcysteine (NAC), an antioxidant agent that replenishes mitochondrial and cytosolic glutathione stores, has been used in the treatment of late acetaminophen-induced ALF and non-acetaminophen-induced ALF. In our unit, NAC was intro