Short-term longitudinal evaluation of cerebral blood flow in mild Alzheimer's disease
β Scribed by G. Tonini; M.F. Shanks; A. Venneri
- Publisher
- Springer Milan
- Year
- 2003
- Tongue
- English
- Weight
- 176 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1590-1874
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Relative regional cerebral blood (rCBF) was measured in 10 patients fulfilling NINCDS-ADRDA criteria for Alzheimer's disease using Tc-99m-HMPAO single photon emission tomography (SPET). In comparison with 1 1 age-matched control subjects, relative rCBF was reduced in lateral and medial temporal area
Regional cerebral blood flow (rCBF) was studied in nine patients with Alzheimer's disease before and after trestment with tacrine. A small but significant improvement in cognitive functioning on the drug was not accompanied by significant changes in rCBF for the group as a whole. However, when the a