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Shock revelations about HLA–DR4 — a shortcut to rheumatoid arthritis?

✍ Scribed by Ollier, Bill


Book ID
109927650
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
212 KB
Volume
2
Category
Article
ISSN
1078-8956

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Susceptibility to rheumatoid arthritis (RA) maps to residues QKRAA/QRRAA in the third hypervariable region of the HLA DRI31 chain. Peptides from the same area of MHC class II molecules are able to modulate the T-cell repertoire by deleting self-reactive T-cells. The Epstein Barr virus glycoprotein g