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HLA—-DR4 is not a requisite for autoimmunity to collagen in rheumatoid arthritis

✍ Scribed by Gary M. Kammer; David E. Trentham

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
484 KB
Volume
27
Category
Article
ISSN
0004-3591

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T cell responses to a human cartilage au
T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis–associated and nonassociated HLA–DR4 alleles
✍ Andrew P. Cope; Salil D. Patel; Frances Hall; Mauro Congia; Henk A. J. M. Hubers 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB 👁 1 views

Objective. To analyze the CD4؉ ؉ ؉ T cell responses to the human cartilage antigen glycoprotein-39 (HCgp-39) in the context of rheumatoid arthritis (RA)-associated (DR␣␤1\*0401) and nonassociated (DR␣␤1\*0402) HLA class II molecules. Methods. Large numbers of HCgp-39-specific T cell hybridomas were