Antibodies to type II collagen and HLA disease susceptibility markers in rheumatoid arthritis
β Scribed by Andrew D. Cook; Alex Stockman; Caroline A. Brand; Brian D. Tait; Ian R. Mackay; Kenneth D. Muirden; Claude C. A. Bernard; Merrill J. Rowley
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 125 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0004-3591
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## Abstract A passive hemagglutination assay was used to detect antibodies to native human collagens and to collagen chains in the sera of 110 rheumatoid patients and those of 75 normal controls. The incidence and titer of anticollagen antibodies in rheumatoid arthritis are high, but in controls th
## Abstract ## Objective To prospectively investigate the effect of the DERAAβencoding HLA alleles on disease susceptibility and severity in a large cohort of patients with rheumatoid arthritis (RA), and to differentiate protective effects from nonpredisposition by comparing subgroups of patients
## Abstract ## Objective To investigate the association of susceptibility and protective HLAβDRB1 alleles with rheumatoid arthritis (RA) and its clinical markers in an Asian population. ## Methods All RA patients (n = 574) and control subjects (n = 392) were Korean. HLAβDRB1 typing and further s