Determination of (R)- and (S)-ketoprofen
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Eichhold, Thomas H.; Bailey, Ruth E.; Tanguay, Suzanne L.; Hoke, Steven H.
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Article
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2000
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John Wiley and Sons
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English
⚖ 113 KB
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A sensitive and selective method was developed for the determination of (R)-ketoprofen ((R)-kt) and (S )-ketoprofen ((S )-kt) in human plasma using chiral liquid chromatography/tandem mass spectrometry (LC/MS/MS). Plasma samples spiked with stable-isotope-labeled [ 13 C 1 , 2 H 3 ]-(R and S )-ketopr