Shared T-cell receptor gene usage in experimental allergic neuritis and encephalomyelitis
โ Scribed by Stefan Jung; Hans-Peter Hartung; Klaus V. Toyka
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 121 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
โฆ Synopsis
Clark and associates El] examined the T-cell receptors (TcR) of Lewis rat T lymphocytes that cause experimental allergic neuritis (EAN), a model of the Guillain-Barre syndrome
๐ SIMILAR VOLUMES
Early studies of murine experimental autoimmune encephalomyelitis (EAE) induced with myelin basic protein (MBP) divide various mouse strains into either "susceptible" or "resistant" phenotypes. Resistance is defined as lack of encephalitogenic responses after active immunization or adoptive transfer
Rats of the Fischer 344 (F344) strain are resistant to experimental allergic encephalomyelitis (EAE) induced by active immunization with guinea pig myelin basic protein (MBP) in complete Freund's adjuvant whereas Lewis (LEW) rats are susceptible even though both strains share the same I-A-like class