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Sfrp1 and Sfrp2 are required for normal male sexual development in mice

✍ Scribed by Nick Warr; Pam Siggers; Debora Bogani; Rachel Brixey; Laura Pastorelli; Laura Yates; Charlotte H. Dean; Sara Wells; Wataru Satoh; Akihiko Shimono; Andy Greenfield


Book ID
116977206
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
689 KB
Volume
326
Category
Article
ISSN
0012-1606

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## Abstract Many developing tissues require programmed cell death (PCD) for proper formation. In mice and __C. elegans__, developmental PCD is regulated by the Bcl‐2 family of proteins. Two __bcl‐2__ genes are encoded in the __Drosophila__ genome (__debcl/dBorg1/Drob‐1/dBok__ and __buffy/dBorg2__)