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Sex-linked histoincompatibility of pituitary isografts in the C57BL strain of mice

✍ Scribed by Kazumasa Hoshino; Judith E. Moore

Publisher
John Wiley and Sons
Year
1968
Tongue
French
Weight
519 KB
Volume
3
Category
Article
ISSN
0020-7136

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✦ Synopsis

Two pituitary glands were isografted, one on each side, into the fourth mammary gland fat pads of intact virgin female mice aged 3 to 6 months; C57BL hosts received grafts from either male or female sibling donors of the same age, and BALBIc hosts from males only. The success or failure of the grafts was determined in three ways: I ) vaginal smears as a clinical criterion, 2 ) gross observation of the transplantation site under anesthesia, and 3 ) histological examinations of the pituitary grafts. The rates of successful pituitary isografts were shown to be: in C57BL hosts, 13/46 (28.3%) from

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