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Severe systemic sclerosis with anti-topoisomerase I Antibodies is associated with an HLA-DRw11 allele

✍ Scribed by Penelope A. Morel; Huan J. Chang; John W. Wilson; Claudia Conte; Susan L. Saidman; Jeffrey D. Bray; David J. Tweardy; Thomas A. Medsger Jr.


Book ID
119145321
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
838 KB
Volume
40
Category
Article
ISSN
0198-8859

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Association of the PTPN22 R620W polymorp
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## Abstract ## Objective To determine any associations of the __PTPN22__ R620W single‐nucleotide polymorphism (SNP) with systemic sclerosis (SSc) or with anticentromere antibody (ACA)–positive or anti–topoisomerase I (anti–topo I) antibody–positive SSc, in a case–control study of US white, black,