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Severe nonspecific X-linked mental retardation caused by a proximally Xp located gene: Intragenic heterogeneity or a new form of X-linked mental retardation?

✍ Scribed by Passos-Bueno, Maria Rita ;Byth, Barbara C. ;Rosenberg, Sergio ;Takata, Reinaldo I. ;Bakker, Egbert ;Beggs, Alan H. ;Pavanello, Rita C. ;Vainzof, Mariz ;Davies, Kay E. ;Zatz, Mayana


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
455 KB
Volume
46
Category
Article
ISSN
0148-7299

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## Linkage analysis was performed on a fourgeneration family with nonspecific mental retardation (MRX59 ). The five affected males, ranging in age from 2 years to 52 years, have a normal facial appearance and mild to severe mental impairment. Four obligate carriers are physically normal and not ret