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Seven Novel Linear Polyketides from Xylaria sp. NCY2

✍ Scribed by Zhi-Yu Hu; Yao-Yao Li; Chun-Hua Lu; Ting Lin; Ping Hu; Yue-Mao Shen


Publisher
John Wiley and Sons
Year
2010
Tongue
German
Weight
180 KB
Volume
93
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Seven novel polyketides, namely, 1‐(xylarenone A)xylariate A (1), xylarioic acid B (2), xylariolide A (3), xylariolide B (4), xylariolide C (5), methyl xylariate C (6), and xylariolide D (7), together with the known one taiwapyrone (8), were isolated from the endophytic fungal strain Xylaria sp. NCY2 of Torreya jackii Chun. Their structures were elucidated by spectroscopic analyses, including 1D‐ and 2D‐NMR experiments, and on the basis of HR‐Q‐TOF mass spectrometry. Antitumor and antibacterial assays of compounds 1–8 were carried out, which show moderate activities.


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