Sesquiterpenoids and Lignans from Ligularia virgaurea spp. oligocephala
✍ Scribed by Ya Li; Yan-Ping Shi
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- German
- Weight
- 76 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
From the BuOH extract of the whole plant of Ligularia virgaurea spp. oligocephala, a series of sesquiterpenes, sesquiterpene glycosides, and lignan glycosides were isolated, including the three new compounds (1__α__)‐1‐hydroxy‐8‐oxo‐eremophila‐6,9‐dien‐12‐oic acid (1), 8‐[(β‐D‐glucopyranosyl)oxy]eremophila‐1(10),8,11‐trien‐2‐one (2), and 4‐[(β‐D‐glucopyranosyl)oxy]pinoresinol (4). Their structures were elucidated by 1D‐ and 2D‐NMR as well as HR‐ESI‐MS analyses, and by comparison of the spectroscopic data with those reported for structurally related compounds.
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## Abstract Two novel sesquiterpene dimers, ligularin A (**1**) and ligulolide D (**2**), and one new sesquiterpenoid, 1__β__,10__α__‐dihydroxy‐6__β__‐[(2‐methylpropyl)oxy]furanoeremophil‐9‐one (**3**), as well as two known sesquiterpenoids, 6__β__‐[(2‐methylpropyl)oxy]‐furanoeremophil‐1(10)‐en‐9‐o
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## Abstract Two novel sesquiterpene dimers, compounds **1** and **2**, were isolated from the rhizome of __Ligularia virgaurea__, together with the six known sesquiterpenoids **3**–**8**. Their structures were established by physico‐chemical and spectroscopic methods, especially by means of 1D‐ and