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Serum α-L-fucosidase activity and early detection of hepatocellular carcinoma : A prospective study of patients with cirrhosis

✍ Scribed by Maria G. Giardina; Margherita Matarazzo; Roberto Morante; Antonio Lucariello; Antonio Varriale; Vincenzo Guardasole; Giulio De Marco

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
103 KB
Volume
83
Category
Article
ISSN
0008-543X

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✦ Synopsis

BACKGROUND.

Serum ␣-L-fucosidase activity is considered a marker of hepatocellular carcinoma. To the authors' knowledge, its clinical usefulness in the early detection of hepatocellular carcinoma in the follow-up of cirrhotic patients has not been reported previously.

METHODS.

The authors prospectively studied serum ␣-L-fucosidase activity, in addition to ␣-fetoprotein and ultrasonography, in a regular screening of 132 cirrhotic patients during an 8-year follow-up.

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