Serum zinc and copper in active rheumatoid arthritis: Correlation with interleukin 1β and tumour necrosis factor α
✍ Scribed by A. Zoli; L. Altomonte; R. Caricchio; A. Galossi; L. Mirone; M. P. Ruffini; M. Magaró
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 415 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0770-3198
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📜 SIMILAR VOLUMES
Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor a (TNFa). Seven of 12 sera from RA patients contained TNFa, while only 1 of those from reactive arthritis patients was positive.
## Abstract ## Objective At sites of inflammation, T cells exert pathologic effects through direct contact with monocyte/macrophages, inducing massive up‐regulation of interleukin‐1 (IL‐1) and tumor necrosis factor α (TNFα). We examined the regulatory effects of IL‐18 on monocyte activation by dir