Platelet-derived growth factor (PDGF) is a 30 kDa protein consisting of disulfide-bonded dimers of Aand B-chains. PDGF receptors are of two types, a-and @-receptors, which are members of the protein-tyrosine kinase family of receptors. The receptors are activated by ligand-induced dimerization, wher
β¦ LIBER β¦
Serum platelet-derived growth factor and endothelin concentrations in human hypercholesterolaemia
β Scribed by Dr P. M. W. BATH; J. F. MARTIN
- Book ID
- 114742141
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 334 KB
- Volume
- 230
- Category
- Article
- ISSN
- 0954-6820
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## Abstract The hormones which support growth, in vitro, of normal, neonatal human foreskin fibroblasts were determined. Wheresas thrombin and hydrocortisone were major growth stimulants, plateletβderived growth factor was not. Human foreskin fibroblasts grew in a serumβfree, biochemically defined