Serum phosphodiesterase I activity in breast cancer patients
โ Scribed by Bender, John W.
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 217 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0098-1532
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โฆ Synopsis
Serum phosphodiesterase I (PDE I) activity was determined in 13 control and 51 breast-cancer patients with various stages of disease. Patients with both localized and metastatic breast cancer had significantly elevated serum PDE I activity. The highest activity was seen in patients with liver metastases. A decline in serum PDE I activity was seen after surgical resection of all known disease.
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Eighty-one women admitted for breast tumor biopsy have been followed sequentially for 12 months. Thirty-one women had clinical stage I and II breast cancer and 50 had benign breast disease. All these women had serum immunoglobulin IgA, IgG, IgM and IgE levels measured by immunodiffusion and radioimm