Serum phosphate as a predictor of outcome in acetaminophen-induced fulminant hepatic failure
โ Scribed by Paul J. Gow; Siddharth Sood; Peter W. Angus
- Book ID
- 111722108
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 47 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0270-9139
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๐ SIMILAR VOLUMES
Results concerning morphological and biochemical changes following intravenous administration of different doses of acetaminophen in dogs are reported. Acetaminophen infusion, as a parenteral solution (500 mg per kg per 90 min), produced fulminant hepatitis characterized by a good correlation betwee
We have established an improved model of fulminant hepatic failure in dogs. Buthionine sulfoximine is used to inactivate glutathione synthesis, and small increments of acetaminophen are given intravenously to maintain the plasma level at approximately 200 pg/ml for 20 hr. This regimen produces sever