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Serum paraoxonase 1 (PON1) lactonase activity is lower in end-stage renal disease patients than in healthy control subjects and increases after hemodialysis

โœ Scribed by Gugliucci, Alejandro; Kinugasa, Eriko; Kotani, Kazuhiko; Caccavello, Russell; Kimura, Satoshi


Book ID
119969577
Publisher
Walter de Gruyter GmbH & Co. KG
Year
2011
Tongue
English
Weight
204 KB
Volume
49
Category
Article
ISSN
1434-6621

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Serum paraoxonase 1 (PON1) lactonase act
โœ Gugliucci, Alejandro; Kinugasa, Eriko; Kotani, Kazuhiko; Caccavello, Russell; Ki ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Walter de Gruyter GmbH & Co. KG ๐ŸŒ English โš– 204 KB

## Abstract **Background:** The mechanism of paraoxonase 1 (PON1) atheroprotective remains elusive. The lactonizing/lactonase activity of PON1 is gaining favor as the most significant in physiology. **Methods:** We studied 42 end-stage renal disease (ESRD) patients undergoing hemodialysis (HD) and