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Serum aspirin esterase activity is lower in end-stage renal disease patients than in healthy control subjects and increases after haemodialysis

✍ Scribed by Gugliucci, A.; Kotani, K.; Kinugasa, E.; Hermo, R.; Caccavello, R.; Kimura, S.

Book ID: 127212505
Publisher: Royal Society of Medicine Press
Year: 2010
Tongue: English
Weight: 130 KB
Volume: 47
Category: Article
ISSN: 0004-5632
DOI: 10.1258/acb.2010.010135

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Serum paraoxonase 1 (PON1) lactonase act

Serum paraoxonase 1 (PON1) lactonase activity is lower in end-stage renal disease patients than in healthy control subjects and increases after hemodialysis

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## Abstract **Background:** The mechanism of paraoxonase 1 (PON1) atheroprotective remains elusive. The lactonizing/lactonase activity of PON1 is gaining favor as the most significant in physiology. **Methods:** We studied 42 end-stage renal disease (ESRD) patients undergoing hemodialysis (HD) and