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Serum levels of folate, homocysteine, and vitamin B12 in head and neck squamous cell carcinoma and in laryngeal leukoplakia

✍ Scribed by Giovanni Almadori; Francesco Bussu; Jacopo Galli; Gabriella Cadoni; Bruno Zappacosta; Silvia Persichilli; Angelo Minucci; Bruno Giardina; Maurizio Maurizi


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
171 KB
Volume
103
Category
Article
ISSN
0008-543X

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A lmadori et al. reported decreased serum folate and increased homocysteine concentrations in patients with head and neck carcinoma compared with healthy nonsmokers or smokers. 1 The authors concluded that these metabolic alterations might promote or derive from disease progression. Similarly, decre

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## Abstract The objectives of this study were to investigate the effects of intratumorally (i.t.) administered recombinant human interleukin‐12 (rhIL‐12) on the distribution and function of B cells in the primary tumors, the locoregional lymph nodes and peripheral blood of head and neck squamous ce