Serum glibenclamide in diabetic patients, and influence of food on the kinetics and effects of glibenclamide
✍ Scribed by G. Sartor; A. Melander; B. Scherstén; E. Wåhlin-Boll
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 533 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0012-186X
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Physical exercise is associated with a fall in serum insulin levels, whereas sulphonylurea administration increases insulin release. To date, the opposing effects of exercise and sulphonylurea administration have not been systematically studied in Type 2 diabetic patients, who are not infrequently t
We have studied the absorption of glibenclamide 10 mg as a single morning dose in 7 patients with non-insulin-dependent diabetes mellitus, comparing normoglycaemic and hyperglycaemic states. The maximal glibenclamide plasma concentrations were significantly higher in the normoglycaemic than in the h