The zymotypic variation of rabbit prealbumin esterases is controlled by three autosomal loci, each with two alleles: Est-1 s and Est-1 s, Est-2 v and Est-2 f', Est-3 D and Est-3 d. Est-1 s gives rise to the three S zones possessing the cocainesterase activity, Est-2 v to the three F zones with atrop
Serum esterase genetics in rabbits. IV. The prealbumin and β-globulin systems
✍ Scribed by L. F. M. Zutphen; M. G. C. W. Bieman; J. Bouw
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 591 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0006-2928
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✦ Synopsis
Discontinuous starch gel electrophoresis revealed a fourth allele of rabbit pre-albumin serum esterase at locus Est-2. This allele is designated Est-2f and appears to be silent. In addition to the prealbumin serum esterases, another serum esterase system was studied in rabbits. This system is localized in the beta-globulin region. Genetic analysis indicated that one locus with two codominant alleles controls the variation in this region. Linkage of this system with Est-1 and Est-2 of the prealbumin serum esterases was demonstrated. Comparison of the arrangement of these esterase loci on linkage group VI with the esterase loci on chromosome 8 of the mouse gives additional support for the theory of evolutionary conservation of chromosomal segments coding for mammalian esterases.
📜 SIMILAR VOLUMES
Rabbit atropinesterase and cocainesterase were studied by starch gel electrophoresis. The enzymes are localized in a region of the gels anodal to the albumins (prealbumin esterases). In this region, three groups of esterase zones ( S, F, and D) can be distinguished. The S and F zones are almost excl