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Serum des-gamma-carboxy prothrombin levels determined by a new generation of sensitive immunoassays in patients with small-sized hepatocellular carcinoma

โœ Scribed by Fumio Nomura; Michikuni Ishijima; Katsuhiko Kuwa; Naomi Tanaka; Toshiaki Nakai; Kunihiko Ohnishi


Book ID
119396091
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
50 KB
Volume
94
Category
Article
ISSN
0002-9270

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## Background: Measurements of serum concentrations of des-gamma-carboxy prothrombin (dcp) are widely used for diagnosing hepatocellular carcinoma (hcc). however, the dcp is not always sensitive enough to detect small hccs. in the current study, the authors investigated the usefulness of dcp in the

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## BACKGROUND. Des-โฅ-carboxy prothrombin (DCP) is an established marker for hepatocellular carcinoma (HCC), but the conventional enzyme immunoassay (EIA) kit lacks adequate sensitivity. Thus, a revised EIA kit with increased sensitivity has been developed. In this kit, the sensitivity has increased