Plasminogen activator inhibitor-1 regula
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Gary Deng; Scott A. Curriden; Geng Hu; Ralf-Peter Czekay; David J. Loskutoff
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Article
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2001
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John Wiley and Sons
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English
β 247 KB
## Abstract Plasminogen activator inhibitorβ1 (PAIβ1) binds to the somatomedin B (SMB) domain of vitronectin. It inhibits the adhesion of U937 cells to vitronectin by competing with the urokinase receptor (uPAR; CD87) on these cells for binding to the same domain. Although the inhibitor also blocks