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Serum cold agglutinin and IgM levels in breast carcinoma

✍ Scribed by Volker E. Dube; Max Haid; Joan Sander Chmiel; Byron Anderson


Publisher
Springer US
Year
1984
Tongue
English
Weight
344 KB
Volume
4
Category
Article
ISSN
0167-6806

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## Abstract Serum protein electrophoresis (SPE) and immunoglobulin levels were studied in 50 patients with breast carcinoma before therapy (17 with stage I disease; 18 stage II; 15 stage III or IV), and in 55 patients after primary lesions were surgically removed and gave no evidence of recurrence.

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## Background: Recently, the extracellular domain of the c-erbb-2 oncogene product (her-2/neu) has been reported to be elevated in the serum of one-fourth of patients with metastatic breast carcinoma. the role of serum c-erbb-2 as a tumor marker, however, is still poorly defined. the purpose of thi

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This investigation was made possible through the generous support of the Friendly Group for Cancer Research. We wish to express our deep appreciation to Bruna Elkan for his skilled technical assistance in preparing the reagent L-tyrosine isopropyl ester and performing all of the tests.