𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Serum antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma

✍ Scribed by Dr. G. Sbolli; A. R. Zanetti; E. Tanzi; L. Cavanna; G. Civardi; F. Fornari; M. Di Stasi; L. Buscarini

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
270 KB
Volume
30
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Antibodies against hepatitis C virus (anti‐HCV) were detected in 60.8% of 78 patients with hepatocellular carcinoma (HCC). Cirrhosis, present in most of the patients, as well as alcohol abuse, age, sex, and α‐fetoprotein were equally distributed in the anti‐HCV‐positive and ‐negative groups. HBsAg positivity was significatively higher in negative anti‐HCV group. By contrast, hepatitis B virus (HBV) antibodies were detected more frequently in positive anti‐HCV patients than in the negative anti‐HCV group. These data must be considered with caution becuase of the small number of HBsAg‐positive patients. It is concluded that the high prevalence of anti‐HCV in patients with HCC may suggest an etiological role of the hepatitis C virus, although in relationship to age, alcohol abuse and cirrhosis, the similarity in the two groups questions this hypothesis.

📜 SIMILAR VOLUMES

Hepatitis C virus antibody in hepatocell
Hepatitis C virus antibody in hepatocellular carcinoma in Taiwan
✍ Jen-Eing Jeng; Jung-Fa Tsai 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 426 KB 👁 1 views

The prevalence of antibody to hepatitis C virus (anti-HCV) was investigated in patients with hepatocellular carcinoma (HCC), and correlated with the clinical features. Anti-HCV was detected in 129 histology or aspiration cytology proven HCC patients and 54 healthy controls. Anti-HCV was examined by

A high prevalence of antibody to the hep
A high prevalence of antibody to the hepatitis C virus in patients with hepatocellular carcinoma in Japan
✍ Kusuya Nishioka; Junnosuke Watanabe; Seiichi Furuta; Eiji Tanaka; Shiro Iino; Hi 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 423 KB 👁 2 views

In Japan, hepatocellular carcinoma (HCC) is one of the most prevalent cancers, with a reported fatality rate showing a consistent and significant increase in the last decade. At most, only 25% of HCC cases are positive for the hepatitis B surface antigen (HBsAg). To investigate a potential role for

Antibodies to hepatitis C virus in patie
Antibodies to hepatitis C virus in patients with mixed cryoglobulinemia
✍ Clodoveo Ferri; Francesco Greco; Giovanni Longombardo; Piero Palla; Adolfo Moret 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 463 KB 👁 2 views

The prevalence of antibodies to hepatitis C virus (HCVAb) was investigated in 52 unselected patients with mixed cryoglobulinemia and in 84 patients with other systemic immunologic diseases. HCVAb were detected by an enzyme-linked immunosorbent assay, and their specificity was evaluated by a recombin

Prevalence of antibody against the core
Prevalence of antibody against the core protein of hepatitis C virus in patients with hepatocellular carcinoma
✍ Yushiro Watanabe; Shizuko Harada; Izumu Saito; Tatsuo Miyamura 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 495 KB 👁 1 views

We have cloned the whole structural region of the hepatitis C virus (HCV) genome and transiently expressed the nucleocapsid protein in animal cells. Since the nucleotide sequences of this region of the HCV genome has been shown to be highly conserved among different HCV isolates, the assay detecting