Serrated adenoma of the colorectum
โ Scribed by J.R. Jass
- Book ID
- 117835025
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 737 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0968-6053
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๐ SIMILAR VOLUMES
Serrated adenoma of the colorectum was a newly proposed entity in 1990, characterized by epithelial neoplasia combining the architectural features of a hyperplastic (metaplastic) polyp with the cytological features of an adenoma. Its histogenesis and natural history still remain unclear. Forty-six s
Serrated adenoma has been recently proposed as a distinct histological lesion of the colorectum. This study examined p53 immunoreactivity, mutations of exons 5-8 of the p53 gene, codon 12 of the Ki-ras gene by PCR-SSCP analyses, and microsatellite instability in 19 serrated adenomas, ten adenocarcin