Serotonin (5-HT) uptake was studied in the blood platelets of 10 patients with Duchenne-type muscular dystrophy (DMD) and 7 age-matched controls. V,,, (maximum number of uptake sites) of platelet 5-HT uptake in the DMD patients was significantly less than that of the normal controls. There was no di
Serotonin uptake by blood platelets of acute schizophrenic patients
โ Scribed by Ilan Modai; Avner Rotman; Hanan Munitz; Shmuel Tjano; Henricus Wijsenbeek
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 324 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
โฆ Synopsis
Active uptake of serotonin by blood platelets of acute schizophrenic patients has been compared to that of a control group. Preliminary results presented in this article indicate that the uptake of the schizophrenic patients was about 40% lower than that of controls. Patients were followed over a period of 5 weeks with no significant change in uptake.
๐ SIMILAR VOLUMES
The active uptake of serotonin (5-HT) by blood platelets of 20 schizophrenic patients and their families was studied. The uptake was studied over a wide range of 5-HT concentrations (0.1-20 ~tM), and K,, and Vmax of the uptake process were calculated. Of 20 patients, 18 exhibited a lower rate of upt
Active uptake of serotonin (5-HT) by blood platelets with bipolar primary affective disorder-bipolar type has been compared to that of their family members and healthy controls, and K~ and Vma x values were calculated for each subject. The uptake of patients' platelets, as reflected by Vmax, was fou