Serotonin Transporters – Structure and Function
✍ Scribed by Gary Rudnick
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 533 KB
- Volume
- 213
- Category
- Article
- ISSN
- 0022-2631
No coin nor oath required. For personal study only.
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## Abstract Renal elimination of anionic drugs, xenobiotics, and toxins is necessary for the survival of mammalian species. This process is mediated by vectorial transport from blood to urine through the cooperative functions of specific transporters in the basolateral and apical membranes of the p
## Abstract Vesicular monoamine transporters (VMAT) are responsible for the uptake of cytosolic monoamines into synaptic vesicles in monoaminergic neurons. Two closely related VMATs with distinct pharmacological properties and tissue distributions have been characterized. VMAT1 is preferentially ex