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Serotonin Transporter Genetic Variation and the Response of the Human Amygdala

✍ Scribed by Hariri, A. R.


Book ID
118279337
Publisher
American Association for the Advancement of Science
Year
2002
Tongue
English
Weight
172 KB
Volume
297
Category
Article
ISSN
0036-8075

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The human serotonin transporter (5-HTT), encoded by a single gene on chromosome 17q11.2, is expressed in brain and blood cells. 5-HTT is implicated in mood and anxiety regulation, and is where antidepressant and antianxiety drugs initially act in the brain. A 5-HTT-linked promoter region (5-HTTLPR)