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Association of human hippocampal neurochemistry, serotonin transporter genetic variation, and anxiety

✍ Scribed by Jürgen Gallinat; Andreas Ströhle; Undine E. Lang; Malek Bajbouj; Peter Kalus; Christiane Montag; Frank Seifert; Catrin Wernicke; Hans Rommelspacher; Herbert Rinneberg; Florian Schubert

Book ID
118489166
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
208 KB
Volume
26
Category
Article
ISSN
1053-8119

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The human serotonin transporter (5-HTT), encoded by a single gene on chromosome 17q11.2, is expressed in brain and blood cells. 5-HTT is implicated in mood and anxiety regulation, and is where antidepressant and antianxiety drugs initially act in the brain. A 5-HTT-linked promoter region (5-HTTLPR)