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Serotonin transporter gene promoter polymorphism predicts SSRI response in generalized social anxiety disorder

✍ Scribed by Murray B. Stein; Soraya Seedat; Joel Gelernter


Book ID
105881572
Publisher
Springer
Year
2006
Tongue
English
Weight
106 KB
Volume
187
Category
Article
ISSN
0033-3158

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It has been suggested that the serotonin transporter (5-hydroxytryptamine-transporter or 5-HTT) may be involved in the pathogenesis of affective disorders. Recently, Collier et al. (1996) found that the frequency of the low-activity short variant (s) of the 5-HTT-linked polymorphic region (5-HTTLPR)