Serotonin transporter gene and manic depressive illness: An association study
✍ Scribed by Frank Bellivier; Jean-Louis Laplanche; Marion Leboyer; Josué Feingold; Corinne Bottos; Jean-François Allilaire; Jean-Marie Launay
- Book ID
- 118511005
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 207 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0006-3223
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We report on an association study between a tetranucleotide repeat polymorphism in the GABR1 gene and manic-depressive illness in a Spanish population. This gene may be an important candidate for bipolar affective disorders since severe GABergic alterations have been described in patients. Although
## Abstract Previous studies have indicated associations between a functional biallelic repetitive element in the 5′ regulatory region of the serotonin transporter gene (5‐HTTLPR) and alcoholic subjects who have either dissocial personality disorder or severe withdrawal symptoms. To replicate these