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Serotonin (5-HT) regulates neurite outgrowth through 5-HT 1A and 5-HT 7 receptors in cultured hippocampal neurons

✍ Scribed by Rojas, Paulina S.; Neira, David; Muñoz, Mauricio; Lavandero, Sergio; Fiedler, Jenny L.

Book ID
121810185
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
423 KB
Volume
92
Category
Article
ISSN
0360-4012

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## Abstract We have studied the effects of 5‐HT~1A~ and 5‐HT~7~ serotonin receptor activation in hippocampal CA3‐CA1 synaptic transmission using patch clamp on mouse brain slices. Application of either 5‐HT or 8‐OH DPAT, a mixed 5‐HT~1A~/5‐HT~7~ receptor agonist, inhibited AMPA receptor‐mediated ex