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Serotonin regulates hippocampal glucocorticoid receptor expression via a 5-HT7 receptor

✍ Scribed by Patricia Laplante; Josie Diorio; Michael J Meaney

Book ID
114134054
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
338 KB
Volume
139
Category
Article
ISSN
0165-3806

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## Abstract We have studied the effects of 5‐HT~1A~ and 5‐HT~7~ serotonin receptor activation in hippocampal CA3‐CA1 synaptic transmission using patch clamp on mouse brain slices. Application of either 5‐HT or 8‐OH DPAT, a mixed 5‐HT~1A~/5‐HT~7~ receptor agonist, inhibited AMPA receptor‐mediated ex