Alpha 2-adrenergic receptors mediate adrenergic stimulation of growth hormone (GH) secretion in the rat. The GH response to the alpha 2-adrenergic agonist clonidine has thus been used as an index of alpha 2-adrenergic receptor responsiveness. Pharmacologic manipulations known to upregulate alpha 2-a
Serotonergic influence on the growth hormone response to clonidine in rat
✍ Scribed by Bo Söderpalm; Lena Andersson; Maria Carlsson; K. Modigh; E. Eriksson
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 482 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1435-1463
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The effect of repeated electroconvulsive shocks (ECS) on growth hormone (GH) secretion was studied in rats. Male Sprague-Dawley animals were given one ECS daily for 10 days under halothane anaesthesia. Control animals were anaesthetised only. GH secretion was studied 24 h after the last ECS or sham
The alpha-adrenergic mechanisms exert a stimulatory influence on the secretion of growth hormone (GH) in the rat. In the present study the alpha receptors involved in GH regulation were characterized with respect to subtype. It was also investigated whether the GH response to alpha receptor agonists