𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Serological and molecular screening for viruses in blood donors from Ntcheu, Malawi: High prevalence of HIV-1 subtype C and of markers of hepatitis B and C viruses

✍ Scribed by D. Candotti; C. Mundy; G. Kadewele; W. Nkhoma; I. Bates; J.-P. Allain

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
108 KB
Volume
65
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

The prevalence of antibodies to human immunodeficiency virus type 1 (HIV-1), hepatitis C virus (HCV), human T lymphotropic virus I (HTLV-I), and hepatitis B (HBV) surface antigen (HBsAg) was determined in blood donors from Ntcheu, Malawi. Each donation was also screened for HIV-1 RNA and HCV RNA. Among 159 blood donations, the prevalence of HIV-1 infection was 10.7%, 8.1% for HBV carriage, 6.8% for anti-HCV, and 2.5% for anti-HTLV-I. HIV-1/HTLV-I and HIV-1/HCV dual infections were observed in 1.2% of the donations. Consequently, 13% of blood donors from Ntcheu should be deferred for retroviral infections and 15% for hepatitis viral infections. Sequence analyses of the HIV-1 strains revealed a relatively homogeneous circulation of subtype C viruses in Malawi. These findings confirm the high endemicity of blood-borne viruses in Malawi and the need for a sensitive viral screening of blood donations to improve blood safety.

📜 SIMILAR VOLUMES

Prevalence of HIV-1 non-B subtypes, syph
Prevalence of HIV-1 non-B subtypes, syphilis, HTLV, and hepatitis B and C viruses among immigrant sex workers in Madrid, Spain
✍ Maite Gutiérrez; Pilar Tajada; Amparo Alvarez; Rosa De Julián; Margarita Baquero 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB

## Abstract Sexually transmitted disease (STD) remains a major public health challenge in developed countries, exacerbated by the advent of the HIV epidemic. The objectives of this study were to assess the prevalence of serological markers of syphilis, HIV‐1/2, HTLV‐I/II, HBV, and HCV infections am

Prevalence of hepatitis B and C serologi
Prevalence of hepatitis B and C serological markers among first-time blood donors in Brazil: A multi-center serosurvey
✍ Maria Claudia Nascimento; Philippe Mayaud; Ester Cerdeira Sabino; Katia Luz Torr 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB

## Abstract Little data are available on the seroprevalence of, and risk factors for hepatitis B and C viruses (HBV and HCV) infection in Latin American countries. A multi‐center serosurvey was conducted among 3,598 first‐time blood donors (65% men) from Sao Paulo, Salvador and Manaus in Brazil. Th

Serological markers of hepatitis B, C, a
Serological markers of hepatitis B, C, and E viruses and human immunodeficiency virus type-1 infections in pregnant women in Bali, Indonesia
✍ I Gede Putu Surya; Karkata Kornia; Tjok Gde Agung Suwardewa; Mulyanto; Fumio Tsu 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 1 views

## Abstract Except for hepatitis B virus (HBV), there have been few data on serological markers of hepatitis viruses such as hepatitis C virus (HCV) and E virus (HEV), and human immunodeficiency virus type‐1 (HIV) in Bali, Indonesia. During 5 months from April to August 2003, sera were collected fr