Serologic response to Epstein-Barr virus antigens in patients with systemic lupus erythematosus: a controlled study
✍ Scribed by Bahar Artım Esen; Gülden Yılmaz; Sami Uzun; Melda Özdamar; Alper Aksözek; Sevil Kamalı; Salih Türkoğlu; Ahmet Gül; Lale Öcal; Orhan Aral; Murat İnanç
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 245 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0172-8172
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## Abstract ## Objective New examples support the concept that host immune responses to pathogenic organisms can act as the nidus for autoimmunity. Two such examples implicate the Epstein‐Barr virus (EBV) in systemic lupus erythematosus (SLE), i.e., data consistent with SLE anti‐Sm and anti–60‐kd
We tested antibody titres against Epstein-Barr virus (EBV) antigens in patients sufrering rrom chronic viral disease and compared them with those determined in sexand age-matched healthy controls. Patient sera showed signs of active EBV infection [antibodies against earl) antigen (EA) and/or viral c