𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antibody response to epstein-barr virus antigens in patients with chronic viral infection

✍ Scribed by Kateřina Roubalová; Jaroslav Roubal; Petr Skopový; Terera Fučiková; Eva Domorázková; V. Vonka

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
480 KB
Volume
25
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

We tested antibody titres against Epstein-Barr virus (EBV) antigens in patients sufrering rrom chronic viral disease and compared them with those determined in sexand age-matched healthy controls. Patient sera showed signs of active EBV infection [antibodies against earl) antigen (EA) and/or viral capsid antigen (VCA) in the IgM or IgA classes] significantly more frequently than the control group. Correspondingly, geometric mean titres ((;MT) of antibodies against all viral antigens were elevated in the patients. The strongest association with EBV was observed in patients whose clinical symptoms closely resembled infectious mononucleosis: 92%) of the Subjects in this subgroup possessed anti-EA and 41 and 25% had IgM and IgA anti-VCA antibody. respectively. Iri patients with signs of lymphoproliferation only and in those suffering from frequent respiratory infections the association with EBV was less marked but still significant. Patients with transient defects in humoral and cellular immunity mounted higher titres against VCA in the IgG class than those without immune defects.

📜 SIMILAR VOLUMES

Antibodies to epstein-barr virus-specifi
Antibodies to epstein-barr virus-specific antigens in patients with hairy-cell leukemia
✍ Kiyoshi Sakamoto; Motohiko Aiba; Isao Katayama; John L. Sullivan; Robert E. Hump 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 480 KB 👁 1 views

## Abstract Antibody titers to Epstein‐Barr virus (EBV)‐specific antigens of 19 patients with hairy‐cell leukemia (HCL) were markedly elevated. All patients showed high titers of IgG anti‐viral capsid antigen (VCA) reactivity equal to or greater than 320 (reciprocal titer). The anti‐VCA reciprocal

Antibodies to Epstein—Barr Viral Antigen
Antibodies to Epstein—Barr Viral Antigens in Early Rheumatoid Arthritis
✍ Stuart L. Silverman; H. Ralph Schumacher 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 332 KB 👁 2 views

## Abstract Antibodies to Epstein—Barr viral (EBV) antigens were studied in 12 patients with early (less than 6 weeks) rheumatoid arthritis (RA) and compared to controls. Geometric mean antibody titers to viral capsid antigen, early antigens, and Epstein—Barr‐associated nuclear antigen (EBNA) were

Impaired cytotoxic T lymphocyte response
Impaired cytotoxic T lymphocyte response to Epstein-Barr virus-infected NK cells in patients with severe chronic active EBV infection
✍ Ikuya Tsuge; Tsuneo Morishima; Hiroshi Kimura; Kiyotaka Kuzushima; Hiroshi Matsu 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB

## Abstract Clinical evidence of a relationship between severe chronic active Epstein‐Barr virus (EBV) infection and clonal expansion of EBV‐infected T or NK cells has been accumulated. In order to clarify pathogenesis of EBV‐infected cell proliferation in patients with severe chronic active EBV in

Epstein-Barr virus and human immunodefic
Epstein-Barr virus and human immunodeficiency virus serological responses and viral burdens in HIV-infected patients treated with HAART
✍ Cathal E. O'Sullivan; RongSheng Peng; Kelly Stefano Cole; Ronald C. Montelaro; T 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB 👁 1 views

## Abstract Epstein‐Barr virus (EBV) associated non‐Hodgkin lymphoma is recognized as a complication of human immunodeficiency virus (HIV) infection. Little is known regarding the influence of highly active antiretroviral therapy (HAART) on the biology of EBV in this population. To characterize the

Antibodies to Epstein-Barr virus-associa
Antibodies to Epstein-Barr virus-associated nuclear antigen and to other viral and non-vical antigens in Hodgkin's Disease
✍ G. Rocchi; G. Tosato; G. Papa; G. Ragona 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 456 KB 👁 1 views

## Abstract Antibody reactivity to Epstein‐Barr virus (EBV)‐associated nuclear antigen (EBNA) was investigated by means of the anticomplement immunofluorescence technique on sera from patients with Hodgkin's disease (HD) and from appropriate controls. Antibody levels to other EBV‐determined antigen

Patients with Epstein Barr virus-positiv
Patients with Epstein Barr virus-positive lymphomas have decreased CD4+ T-cell responses to the viral nuclear antigen 1
✍ Kevin N. Heller; Frida Arrey; Peter Steinherz; Carol Portlock; Amy Chadburn; Kar 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 457 KB 👁 1 views

## Abstract Epstein Barr virus (EBV) causes lymphomas in immune competent and, at increased frequencies, in immune compromised patients. In the presence of an intact immune system, EBV‐associated lymphomas express in most cases only 3 or fewer EBV antigens at the protein level, always including the