Serine Protease Mechanism and Specificity
โ Scribed by Hedstrom, Lizbeth
- Book ID
- 120341364
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 306 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0009-2665
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Conservation of clusters of buried water molecules is a structural motif present throughout the serine protease family. Frequently, these clusters are shaped as water channels forming extensive hydrogen-bonding networks linked to the protein backbone. The most conspicuous example is the water channe
Isocoumarins are potent mechanism-based heterocyclic irreversible inhibitors for a variety of serine proteases. Most serine proteases are inhibited by the general serine protease inhibitor 3,4-dichloroisocoumarin, whereas isocoumarins containing hydrophobic 7-acylamino groups are potent inhibitors f