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Serine 48 in Initiation Factor 2α (eIF2α) Is Required for High-Affinity Interaction between eIF2α(P) and eIF2B †

✍ Scribed by Sudhakar, Akulapalli; Krishnamoorthy, Thanuja; Jain, Anjali; Chatterjee, Udayan; Hasnain, Seyed E.; Kaufman, Randal J.; Ramaiah, Kolluru V. A.


Book ID
126817793
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
262 KB
Volume
38
Category
Article
ISSN
0006-2960

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## Abstract ## BACKGROUND Stimulation of resting cells by growth factors leads to an increase in the rate of protein synthesis, which is necessary for cell growth and division. Translation initiation factor eIF‐2α is one of the key translation factors mediating the effects of growth factors on pro