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Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression

✍ Scribed by Chao, Connie; Herr, Deron; Chun, Jerold; Xu, Yang

Book ID
110031552
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
222 KB
Volume
0
Category
Article
ISSN
0261-4189

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## Abstract ## BACKGROUND Akt/protein kinase B (PKB), which is included in phosphatidyl inositol‐3‐OH kinase (PI3K) signaling, controls many intracellular processes, such as the suppression of apoptosis and the promotion of the cell cycle. Therefore, the authors investigated phosphorylated Akt (Se