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Sequential moderate-dose methotrexate and 5-fluorouracil in advanced gastric adenocarcinoma

✍ Scribed by R. Dickinson; P. Presgrave; J. Levi; S. Milliken; R. Woods

Book ID: 104684451
Publisher: Springer
Year: 1989
Tongue: English
Weight: 198 KB
Volume: 24
Category: Article
ISSN: 0344-5704
DOI: 10.1007/bf00254110

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## Abstract Thirty patients with advanced measurable colorectal cancer were randomized to receive either methotrexate (MTX) 200 mg/m^2^ or 40 mg/m^2^, followed in four hours by 5‐fluorouracil (5‐FU) 600 mg/m^2^. Patients receiving the higher dose MTX were given leucovorin rescue 24 hours later. Eig